Compound Clusters
25 mechanistic compound clusters computed via Louvain community detection on the BiohacksAI target interaction graph. Compounds within each cluster share molecular target interactions, suggesting mechanistic similarity and potential combinatorial synergy.
SYK Modulators
320 compoundscohesion 0.059
Androgen Receptor235 compoundscohesion 0.130
5-HYDROXYTRYPTAMINE Modulators234 compoundscohesion 0.111
CYP2C19 Modulators185 compoundscohesion 0.114
CA2 Modulators43 compoundscohesion 0.225
OPRM1 Modulators29 compoundscohesion 0.370
GRIN2A Modulators14 compoundscohesion 0.360
MUS Modulators11 compoundscohesion 0.136
GLUTATHIONE Modulators11 compoundscohesion 0.379
ABCC3 Modulators9 compoundscohesion 0.270
GABRA2 Modulators9 compoundscohesion 0.452
GPBAR1 Modulators9 compoundscohesion 0.314
SLCO2B1 Modulators6 compoundscohesion 0.355
PTGER1 Modulators5 compoundscohesion 0.306
NOS1 Modulators5 compoundscohesion 0.562
TACR3 Modulators5 compoundscohesion 0.550
SLC22A6 Modulators5 compoundscohesion 0.462
AVPR1B Modulators5 compoundscohesion 0.606
SCN4A Modulators4 compoundscohesion 0.358
P2RY4 Modulators4 compoundscohesion 0.354
CTBP1 Modulators3 compoundscohesion 1.000
MC1R Modulators3 compoundscohesion 0.636
HRH4 Modulators3 compoundscohesion 0.697
CYSLTR2 Modulators3 compoundscohesion 0.473
P2RY14 Modulators3 compoundscohesion 0.411