What compounds affect the Fatty acids pathway?

326 compounds in the BiohacksAI corpus have documented interactions with genes in the Fatty acids pathway (Reactome ID: R-HSA-211935). These compounds target 4 genes within this pathway.

What genes are in the Fatty acids pathway?

The Fatty acids pathway involves 4 genes. Key genes include: CYP2A13, CYP2B6, CYP2D6, CYP2J2.

Fatty acids

REACTOME PATHWAY

Reactome: R-HSA-2119354 genes326 compounds

The Fatty acids pathway (Reactome ID: R-HSA-211935) involves 4 genes and is affected by 326 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

CYP2A13 CYP2B6 CYP2D6 CYP2J2

Compounds Affecting Fatty acids

#	Compound	Targets Hit	Studies
1	Methoxsalen	—	300
2	Astemizole Antihistamine drug now withdrawn from	—	280
3	Danazol	—	298
4	Miconazole	—	298
5	Flunarizine Flunarizine is	—	299
6	Ritonavir	—	298
7	cbd	—	298
8	cannabidiol	—	296
9	Ethinyl Estradiol	—	300
10	Triamcinolone	—	300
11	Quinidine	—	298
12	Yohimbine	—	299
13	Dextromethorphan Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of	—	296
14	Chlorhexidine	—	299
15	Cyproheptadine	—	299
16	Maprotiline	—	299
17	Oxymetazoline	—	298
18	Nortriptyline	—	295
19	Kaempferols	—	300
20	Amoxapine	—	259
21	Celecoxib	—	295
22	Fluspirilene	—	74
23	Loratadine	—	296
24	Perphenazine	—	297
25	Piribedil	—	300
26	Riboflavin Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables.	—	297
27	Timolol	—	298
28	Tolazamide	—	169
29	Buspirone	—	299
30	Clotrimazole	—	296
31	Domperidone	—	299
32	doxylamine succinate	—	35
33	Ethoxyquin Antioxidant; also	—	180
34	Phentolamine	—	300
35	Piperonyl Butoxide	—	300
36	Methylene Blue	—	200
37	Progesterone	—	299
38	Cimetidine	—	299
39	clofilium tosylate	—	4
40	Clonidine	—	299
41	Physostigmine	—	300
42	Ethidium	—	300
43	lidoflazine	—	278
44	Melphalan	—	300
45	Vitamin K 3	—	300
46	Metoclopramide	—	297
47	Niacin	—	295
48	oxatomide [Supplementary Concept] structure;	—	128
49	Phenelzine	—	2
50	Physostigmine	—	299

About the Fatty acids Pathway

The Fatty acids pathway is catalogued in Reactome (ID: R-HSA-211935) and involves 4 genes. In the BiohacksAI corpus, 326 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CYP2A13, CYP2B6, CYP2D6, CYP2J2.