What genes are in the Regulation of HMOX1 expression and activity pathway?

The Regulation of HMOX1 expression and activity pathway involves 1 genes. Key genes include: NFE2L2.

Regulation of HMOX1 expression and activity

Q: What compounds affect the Regulation of HMOX1 expression and activity pathway?

202 compounds in the BiohacksAI corpus have documented interactions with genes in the Regulation of HMOX1 expression and activity pathway (Reactome ID: R-HSA-9707587). These compounds target 1 genes within this pathway.

REACTOME PATHWAY

Reactome: R-HSA-97075871 genes202 compounds

The Regulation of HMOX1 expression and activity pathway (Reactome ID: R-HSA-9707587) involves 1 genes and is affected by 202 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

NFE2L2

Compounds Affecting Regulation of HMOX1 expression and activity

#	Compound	Targets Hit	Studies
1	Resveratrol	—	298
2	Colchicine	—	300
3	Vitamin	—	295
4	Azacitidine	—	298
5	Azacitidine	—	300
6	Genistein	—	300
7	Apigenin 5,7,4'-trihydroxy-flavone,	—	300
8	alpha-Linolenic Acid	—	300
9	Oxymetholone	—	298
10	Rotenone	—	300
11	Methylene Blue	—	200
12	Ethoxyquin Antioxidant; also	—	180
13	Nitrofurazone	—	300
14	Quercetin	—	300
15	Azathioprine	—	300
16	Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as	—	300
17	Mestranol	—	300
18	methoprene	—	300
19	Niclosamide	—	299
20	Phenelzine	—	2
21	vinblastine sulfate	—	81
22	chrysin	—	300
23	alyssin [Supplementary Concept]	—	300
24	Digitoxin	—	300
25	Digoxin	—	299
26	Flutamide	—	298
27	Hexachlorophene	—	300
28	Linoleic Acid	—	300
29	Vitamin K 3	—	300
30	Nitrofurantoin	—	297
31	Ouabain	—	300
32	Podophyllotoxin	—	14
33	Thiabendazole 2-Substituted benzimidazole first introduced in 1962. It is active against	—	299
34	Toxaphene	—	299
35	DEAD-box RNA Helicases	—	169
36	Thioctic Acid	—	298
37	amlexanox	—	96
38	Bortezomib	—	300
39	Chlormadinone Acetate	—	300
40	Ethidium	—	300
41	Feprazone	—	63
42	Idazoxan	—	300
43	Leflunomide	—	297
44	Nocodazole Nocodazole is	—	215
45	Oxyphenbutazone	—	300
46	Thioctic Acid	—	300
47	Caffeine	—	299
48	propyl gallate	—	261
49	Ascorbic Acid	—	299
50	Methotrexate	—	289

About the Regulation of HMOX1 expression and activity Pathway

The Regulation of HMOX1 expression and activity pathway is catalogued in Reactome (ID: R-HSA-9707587) and involves 1 genes. In the BiohacksAI corpus, 202 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include NFE2L2.