What genes are in the NFE2L2 regulating inflammation associated genes pathway?

The NFE2L2 regulating inflammation associated genes pathway involves 4 genes. Key genes include: CCL2, CREBBP, EP300, NFE2L2.

NFE2L2 regulating inflammation associated genes

Q: What compounds affect the NFE2L2 regulating inflammation associated genes pathway?

207 compounds in the BiohacksAI corpus have documented interactions with genes in the NFE2L2 regulating inflammation associated genes pathway (Reactome ID: R-HSA-9818026). These compounds target 4 genes within this pathway.

REACTOME PATHWAY

Reactome: R-HSA-98180264 genes207 compounds

The NFE2L2 regulating inflammation associated genes pathway (Reactome ID: R-HSA-9818026) involves 4 genes and is affected by 207 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

CCL2 CREBBP EP300 NFE2L2

Compounds Affecting NFE2L2 regulating inflammation associated genes

#	Compound	Targets Hit	Studies
1	Colchicine	—	300
2	Nocodazole Nocodazole is	—	215
3	Papaverine	—	299
4	Resveratrol	—	298
5	Vitamin	—	295
6	Azacitidine	—	298
7	Azacitidine	—	300
8	Genistein	—	300
9	Apigenin 5,7,4'-trihydroxy-flavone,	—	300
10	alpha-Linolenic Acid	—	300
11	Oxymetholone	—	298
12	Rotenone	—	300
13	Methylene Blue	—	200
14	Ethoxyquin Antioxidant; also	—	180
15	Nitrofurazone	—	300
16	Quercetin	—	300
17	Azathioprine	—	300
18	Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as	—	300
19	Mestranol	—	300
20	methoprene	—	300
21	Niclosamide	—	299
22	Phenelzine	—	2
23	vinblastine sulfate	—	81
24	chrysin	—	300
25	alyssin [Supplementary Concept]	—	300
26	Digitoxin	—	300
27	Digoxin	—	299
28	Flutamide	—	298
29	Hexachlorophene	—	300
30	Linoleic Acid	—	300
31	Vitamin K 3	—	300
32	Nitrofurantoin	—	297
33	Ouabain	—	300
34	Podophyllotoxin	—	14
35	Thiabendazole 2-Substituted benzimidazole first introduced in 1962. It is active against	—	299
36	Toxaphene	—	299
37	DEAD-box RNA Helicases	—	169
38	Thioctic Acid	—	298
39	amlexanox	—	96
40	Bortezomib	—	300
41	Chlormadinone Acetate	—	300
42	Ethidium	—	300
43	Feprazone	—	63
44	Idazoxan	—	300
45	Leflunomide	—	297
46	Oxyphenbutazone	—	300
47	Thioctic Acid	—	300
48	Caffeine	—	299
49	propyl gallate	—	261
50	Ascorbic Acid	—	299

About the NFE2L2 regulating inflammation associated genes Pathway

The NFE2L2 regulating inflammation associated genes pathway is catalogued in Reactome (ID: R-HSA-9818026) and involves 4 genes. In the BiohacksAI corpus, 207 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CCL2, CREBBP, EP300, NFE2L2.