What compounds target ABCB1?

BiohacksAI has identified 145 compounds that interact with ABCB1 (ATP binding cassette subfamily B member 1). Top compounds include: Reserpine, Quinidine, Astemizole Antihistamine drug now withdrawn from, Clotrimazole, Testosterone. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is ABCB1 (ATP binding cassette)?

ABCB1 is ATP binding cassette subfamily B member 1. It is a molecular target for 145 compounds documented in PubMed bioassay data. UniProt ID: P08183. NCBI Gene ID: 5243.

ABCB1

MOLECULAR TARGET

ATP binding cassette subfamily B member 1

UniProt: P08183 NCBI Gene: 5243145 compounds

ABCB1 (ATP binding cassette subfamily B member 1) is targeted by 145 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting ABCB1

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	Reserpine	2.83	16
2	Quinidine	2.48	11
3	Astemizole Antihistamine drug now withdrawn from	1.79	5
4	Clotrimazole	1.79	5
5	Testosterone	1.61	4
6	Emetine	1.61	4
7	Progesterone	1.39	3
8	Simvastatin	1.39	3
9	Carvedilol	1.39	3
10	Colchicine	1.39	3
11	Digitoxigenin 3 beta,14-Dihydroxy-5 beta-card-20(22)enolide.	1.39	3
12	Miconazole	1.39	3
13	Nocodazole Nocodazole is	1.39	3
14	Podophyllotoxin	1.39	3
15	Ritonavir	1.39	3
16	egcg	1.10	2
17	2-Methoxyestradiol	1.10	2
18	Methotrexate	1.10	2
19	Anisomycin	1.10	2
20	Azathioprine	1.10	2
21	Bromocriptine	1.10	2
22	Calcimycin	1.10	2
23	cycloheximide	1.10	2
24	Danazol	1.10	2
25	Daunorubicin	1.10	2
26	Delavirdine	1.10	2
27	Demecolcine	1.10	2
28	Digoxigenin 3 beta,12 beta,14-Trihydroxy-5 beta-card-20(22)-enolide.	1.10	2
29	Digoxin	1.10	2
30	Equilin	1.10	2
31	Levonorgestrel	1.10	2
32	Lovastatin	1.10	2
33	Nandrolone C18 steroid with androgenic and anabolic properties. It is generally prepared from alkyl ethers of ESTRADIOL to resemble TESTOSTERONE but less	1.10	2
34	Niclosamide	1.10	2
35	Norgestrel	1.10	2
36	Nortriptyline	1.10	2
37	streptonigrin	1.10	2
38	Strophanthidin 3 beta,5,14-Trihydroxy-19-oxo-5 beta-card-20(22)-enolide.	1.10	2
39	Tubercidin	1.10	2
40	tyrphostin 9	1.10	2
41	Valinomycin	1.10	2
42	vinblastine sulfate	1.10	2
43	Vincristine	1.10	2
44	Apigenin 5,7,4'-trihydroxy-flavone,	0.69	1
45	Budesonide	0.69	1
46	chrysin	0.69	1
47	Kaempferols	0.69	1
48	Thyroxine	0.69	1
49	Piracetam	0.69	1
50	Quercetin	0.69	1

Showing top 50 of 145 compounds. Use the BiohacksAI search to explore all ABCB1 modulators.

About ABCB1 as a Drug Target

ABCB1 (ATP binding cassette subfamily B member 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 145 compounds with documented ABCB1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

ABCB1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.