ACVR2B
MOLECULAR TARGETactivin A receptor type 2B
ACVR2B (activin A receptor type 2B) is targeted by 14 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting ACVR2B
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | alvocidib | 4.52 | 91 |
| 2 | pazopanib | 3.69 | 39 |
| 3 | sb 202190 | 3.64 | 37 |
| 4 | tae 684 | 3.43 | 30 |
| 5 | saracatinib | 3.33 | 27 |
| 6 | jnj 7706621 | 3.09 | 21 |
| 7 | lestaurtinib | 3.04 | 20 |
| 8 | plx 4720 | 2.71 | 14 |
| 9 | kw 2449 | 2.64 | 13 |
| 10 | ast 487 | 2.56 | 12 |
| 11 | azd 7762 | 2.30 | 9 |
| 12 | gsk 1070916 | 2.20 | 8 |
| 13 | Axitinib | 0.69 | 1 |
| 14 | Dasatinib | 0.69 | 1 |
About ACVR2B as a Drug Target
ACVR2B (activin A receptor type 2B) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 14 compounds with documented ACVR2B interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
ACVR2B inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.