ADAMTS5
MOLECULAR TARGETADAM metallopeptidase with thrombospondin type 1 motif 5
ADAMTS5 (ADAM metallopeptidase with thrombospondin type 1 motif 5) is targeted by 7 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting ADAMTS5
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | epigalocatechin gallate | 5.40 | 220 |
| 2 | epicatechin gallate | 3.95 | 51 |
| 3 | marimastat | 3.47 | 31 |
| 4 | ilomastat | 3.40 | 29 |
| 5 | pyrogallol | 3.14 | 22 |
| 6 | egcg | 0.69 | 1 |
| 7 | piceatannol | 0.69 | 1 |
About ADAMTS5 as a Drug Target
ADAMTS5 (ADAM metallopeptidase with thrombospondin type 1 motif 5) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 7 compounds with documented ADAMTS5 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
ADAMTS5 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.