ADORA2B
MOLECULAR TARGETadenosine A2b receptor
ADORA2B (adenosine A2b receptor) is targeted by 24 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting ADORA2B
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | neca | 4.86 | 128 |
| 2 | 13 dipropyl 8 cyclopentylxanthine dpcpx | 4.57 | 96 |
| 3 | n6 cyclopentyladenosine | 4.28 | 71 |
| 4 | ib meca | 4.01 | 54 |
| 5 | zm 241385 | 3.87 | 47 |
| 6 | pentoxifylline | 3.56 | 34 |
| 7 | istradefylline | 3.50 | 32 |
| 8 | cgs 15943 | 3.47 | 31 |
| 9 | sch 58261 | 3.40 | 29 |
| 10 | xanthine amine congener | 3.37 | 28 |
| 11 | 8 phenyl theophylline | 3.26 | 25 |
| 12 | mivebresib | 3.00 | 19 |
| 13 | enprofylline | 2.94 | 18 |
| 14 | methylthioadenosine | 2.94 | 18 |
| 15 | psilocin | 2.77 | 15 |
| 16 | rolofylline | 2.71 | 14 |
| 17 | 2-Chloroadenosine 2-Chloroadenosine. | 2.64 | 13 |
| 18 | aristeromycin | 2.64 | 13 |
| 19 | Adenosine | 2.08 | 7 |
| 20 | tozadenant | 2.08 | 7 |
| 21 | ciforadenant | 1.95 | 6 |
| 22 | Caffeine | 1.79 | 5 |
| 23 | rs mefloquine | 1.79 | 5 |
| 24 | st1535 | 1.79 | 5 |
About ADORA2B as a Drug Target
ADORA2B (adenosine A2b receptor) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 24 compounds with documented ADORA2B interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
ADORA2B inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.