What compounds target ADRB1?

BiohacksAI has identified 44 compounds that interact with ADRB1 (adrenoceptor beta 1). Top compounds include: Propranolol, Isoproterenol Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on, Atenolol, Alprenolol, Norepinephrine Precursor of epinephrine that is secreted by. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is ADRB1 (adrenoceptor beta 1)?

ADRB1 is adrenoceptor beta 1. It is a molecular target for 44 compounds documented in PubMed bioassay data. UniProt ID: P08588. NCBI Gene ID: 153.

ADRB1

MOLECULAR TARGET

adrenoceptor beta 1

UniProt: P08588 NCBI Gene: 15344 compounds

ADRB1 (adrenoceptor beta 1) is targeted by 44 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting ADRB1

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	Propranolol	3.71	40
2	Isoproterenol Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on	3.64	37
3	Atenolol	2.94	18
4	Alprenolol	2.56	12
5	Norepinephrine Precursor of epinephrine that is secreted by	2.56	12
6	Practolol	2.48	11
7	Timolol	2.48	11
8	Pindolol	2.40	10
9	Epinephrine	2.30	9
10	Sotalol	2.30	9
11	Acebutolol	1.79	5
12	Bisoprolol	1.79	5
13	Bupranolol	1.79	5
14	Xamoterol	1.79	5
15	Bunolol	1.61	4
16	Carteolol	1.61	4
17	Carvedilol	1.61	4
18	Levalbuterol	1.39	3
19	Levalbuterol	1.39	3
20	Celiprolol	1.39	3
21	Quipazine	1.39	3
22	Fenoterol	1.10	2
23	Labetalol	1.10	2
24	Lysergic Acid Diethylamide Semisynthetic derivative of ergot (Claviceps purpurea). It has complex effects on serotonergic systems including antagonism at some peripheral serotonin receptors, both agonist and antagonist actions at central nervous system serotonin receptors, and possibly effects on serotonin turnover. It is	1.10	2
25	Nadolol	1.10	2
26	Prenalterol	1.10	2
27	Sertraline	0.69	1
28	Aripiprazole	0.69	1
29	Benzethonium Bactericidal cationic quaternary ammonium surfactant used as	0.69	1
30	Bromocriptine	0.69	1
31	Chlorhexidine	0.69	1
32	cinacalcet	0.69	1
33	Clenbuterol	0.69	1
34	Codeine	0.69	1
35	Lisuride	0.69	1
36	Methylergonovine	0.69	1
37	Nebivolol	0.69	1
38	Noscapine	0.69	1
39	Nylidrin	0.69	1
40	Oxprenolol	0.69	1
41	Phenylephrine	0.69	1
42	Ranolazine	0.69	1
43	Tamsulosin	0.69	1
44	Tetrahydropapaveroline	0.69	1

About ADRB1 as a Drug Target

ADRB1 (adrenoceptor beta 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 44 compounds with documented ADRB1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

ADRB1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.