Question 1

What compounds target ADRB3?

Accepted Answer

BiohacksAI has identified 31 compounds that interact with ADRB3 (adrenoceptor beta 3). Top compounds include: Isoproterenol Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on, Propranolol, Norepinephrine Precursor of epinephrine that is secreted by, Alprenolol, Epinephrine. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

Question 2

What is ADRB3 (adrenoceptor beta 3)?

Accepted Answer

ADRB3 is adrenoceptor beta 3. It is a molecular target for 31 compounds documented in PubMed bioassay data. UniProt ID: P13945. NCBI Gene ID: 155.

#	Compound	Confidence	Active Assays
1	Isoproterenol Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on	3.53	33
2	Propranolol	2.94	18
3	Norepinephrine Precursor of epinephrine that is secreted by	2.20	8
4	Alprenolol	1.79	5
5	Epinephrine	1.61	4
6	Practolol	1.61	4
7	Pindolol	1.39	3
8	Sotalol	1.39	3
9	Bisoprolol	1.10	2
10	Bunolol	1.10	2
11	Bupranolol	1.10	2
12	Carvedilol	1.10	2
13	Ritodrine	1.10	2
14	Levalbuterol	0.69	1
15	Simvastatin	0.69	1
16	Acebutolol	0.69	1
17	Levalbuterol	0.69	1
18	Aripiprazole	0.69	1
19	Atenolol	0.69	1
20	Carteolol	0.69	1
21	Celecoxib	0.69	1
22	Celiprolol	0.69	1
23	Clotrimazole	0.69	1
24	Dihydroergotamine	0.69	1
25	Fenoterol	0.69	1
26	Labetalol	0.69	1
27	Loratadine	0.69	1
28	Nadolol	0.69	1
29	Phenylephrine	0.69	1
30	Tetrahydropapaveroline	0.69	1
31	Timolol	0.69	1

BiohacksAI

ADRB3

Compounds Targeting ADRB3

About ADRB3 as a Drug Target