What compounds target AHR?

BiohacksAI has identified 89 compounds that interact with AHR (aryl hydrocarbon receptor). Top compounds include: Carbaryl, Methylcholanthrene, Thiabendazole 2-Substituted benzimidazole first introduced in 1962. It is active against, Diuron, Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is AHR (aryl hydrocarbon receptor)?

AHR is aryl hydrocarbon receptor. It is a molecular target for 89 compounds documented in PubMed bioassay data. UniProt ID: P35869. NCBI Gene ID: 196.

AHR

MOLECULAR TARGET

aryl hydrocarbon receptor

UniProt: P35869 NCBI Gene: 19689 compounds

AHR (aryl hydrocarbon receptor) is targeted by 89 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting AHR

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	Carbaryl	2.20	8
2	Methylcholanthrene	2.08	7
3	Thiabendazole 2-Substituted benzimidazole first introduced in 1962. It is active against	2.08	7
4	Diuron	1.95	6
5	Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as	1.95	6
6	Ethidium	1.95	6
7	Diflubenzuron	1.79	5
8	Edaravone	1.79	5
9	Leflunomide	1.79	5
10	Linuron	1.79	5
11	Reserpine	1.79	5
12	Genistein	1.61	4
13	Thyroxine	1.61	4
14	Methylene Blue	1.61	4
15	Quercetin	1.61	4
16	Carboxin	1.61	4
17	Secologanin Tryptamine Alkaloids Compounds formed by condensation of secologanin with tryptamine resulting in	1.61	4
18	Isoniazid Antibacterial agent used primarily as	1.61	4
19	Vitamin K 3	1.61	4
20	Niclosamide	1.61	4
21	Phenelzine	1.61	4
22	Sulindac	1.61	4
23	Thyroxine	1.61	4
24	chrysin	1.39	3
25	Kaempferols	1.39	3
26	propyl gallate	1.39	3
27	Resveratrol	1.39	3
28	Nisoldipine	1.39	3
29	Picloram	1.39	3
30	Triiodothyronine	1.39	3
31	Night Vision Function of	1.10	2
32	vinpocetine	1.10	2
33	Vitamin K 2	1.10	2
34	2-Acetylaminofluorene	1.10	2
35	amlexanox	1.10	2
36	Axitinib	1.10	2
37	Azathioprine	1.10	2
38	Clobetasol	1.10	2
39	clonixin	1.10	2
40	Clotrimazole	1.10	2
41	Ethoxyquin Antioxidant; also	1.10	2
42	Febuxostat	1.10	2
43	Imatinib Mesylate	1.10	2
44	indirubin	1.10	2
45	Lumefantrine	1.10	2
46	methoprene	1.10	2
47	Methoxsalen	1.10	2
48	Naphazoline	1.10	2
49	Nicergoline	1.10	2
50	ninhydrin	1.10	2

Showing top 50 of 89 compounds. Use the BiohacksAI search to explore all AHR modulators.

About AHR as a Drug Target

AHR (aryl hydrocarbon receptor) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 89 compounds with documented AHR interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

AHR inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.