APEX1
MOLECULAR TARGETapurinic/apyrimidinic endodeoxyribonuclease 1
APEX1 (apurinic/apyrimidinic endodeoxyribonuclease 1) is targeted by 6 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting APEX1
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | tanshinone iia | 3.74 | 41 |
| 2 | thiolactomycin | 3.09 | 21 |
| 3 | mitoxantrone hydrochloride | 2.30 | 9 |
| 4 | lucanthone | 2.20 | 8 |
| 5 | Aurintricarboxylic Acid | 1.39 | 3 |
| 6 | myricetin-3-O-galactopyranoside [Supplementary Concept] | 1.10 | 2 |
About APEX1 as a Drug Target
APEX1 (apurinic/apyrimidinic endodeoxyribonuclease 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 6 compounds with documented APEX1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
APEX1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.