What compounds target AR?

BiohacksAI has identified 296 compounds that interact with AR (androgen receptor). Top compounds include: Dihydrotestosterone, Progesterone, Testosterone, Medroxyprogesterone Acetate, Spironolactone. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is AR (androgen receptor)?

AR is androgen receptor. It is a molecular target for 296 compounds documented in PubMed bioassay data. UniProt ID: AAI32976. NCBI Gene ID: 367.

AR

MOLECULAR TARGET

androgen receptor

UniProt: AAI32976 NCBI Gene: 367296 compounds

AR (androgen receptor) is targeted by 296 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting AR

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	Dihydrotestosterone	4.62	100
2	Progesterone	3.66	38
3	Testosterone	3.53	33
4	Medroxyprogesterone Acetate	3.37	28
5	Spironolactone	3.33	27
6	Flutamide	3.30	26
7	Levonorgestrel	3.18	23
8	Norgestrel	3.18	23
9	Androstenedione	3.04	20
10	Ethinyl Estradiol	3.00	19
11	Testosterone Propionate	3.00	19
12	Prednisolone	2.94	18
13	Corticosterone	2.89	17
14	Budesonide	2.83	16
15	Lynestrenol	2.83	16
16	Methyltestosterone	2.83	16
17	Oxymetholone	2.83	16
18	Prednisone	2.83	16
19	Danazol	2.77	15
20	Estrone	2.77	15
21	Norethindrone	2.77	15
22	Ethisterone 17 alpha-Hydroxypregn-4-en-20-yn-3-one.	2.71	14
23	Ethynodiol Diacetate	2.71	14
24	Fluoxymesterone	2.71	14
25	Nandrolone C18 steroid with androgenic and anabolic properties. It is generally prepared from alkyl ethers of ESTRADIOL to resemble TESTOSTERONE but less	2.64	13
26	cycloheximide	2.56	12
27	Ethidium	2.56	12
28	Ouabain	2.56	12
29	Hydrocortisone	2.48	11
30	Dehydroepiandrosterone	2.48	11
31	Betamethasone	2.48	11
32	Chlormadinone Acetate	2.48	11
33	Dactinomycin	2.48	11
34	Dehydroepiandrosterone	2.48	11
35	Fluorometholone	2.48	11
36	Hydrocortisone	2.48	11
37	Desoxycorticosterone	2.40	10
38	Digoxin	2.40	10
39	Disulfiram	2.40	10
40	Finasteride	2.40	10
41	Methylprednisolone	2.40	10
42	vinblastine sulfate	2.40	10
43	17-alpha-Hydroxyprogesterone	2.30	9
44	Azacitidine	2.30	9
45	Azacitidine	2.30	9
46	Canrenone	2.30	9
47	Chlorhexidine	2.30	9
48	Cortisone	2.30	9
49	Estriol	2.30	9
50	Ethylestrenol	2.30	9

Showing top 50 of 296 compounds. Use the BiohacksAI search to explore all AR modulators.

About AR as a Drug Target

AR (androgen receptor) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 296 compounds with documented AR interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

AR inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.