What compounds target CA12?

BiohacksAI has identified 36 compounds that interact with CA12 (carbonic anhydrase 12). Top compounds include: Sulfanilamide, Indapamide, Phenol, Celecoxib, Chlorthalidone. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is CA12 (carbonic anhydrase 12)?

CA12 is carbonic anhydrase 12. It is a molecular target for 36 compounds documented in PubMed bioassay data. UniProt ID: O43570. NCBI Gene ID: 771.

CA12

MOLECULAR TARGET

carbonic anhydrase 12

UniProt: O43570 NCBI Gene: 77136 compounds

CA12 (carbonic anhydrase 12) is targeted by 36 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting CA12

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	Sulfanilamide	2.40	10
2	Indapamide	2.20	8
3	Phenol	2.20	8
4	Celecoxib	1.95	6
5	Chlorthalidone	1.95	6
6	chrysin	1.39	3
7	benzolamide	1.39	3
8	Furosemide	1.39	3
9	Probenecid	1.39	3
10	Zonisamide	1.39	3
11	caffeic acid	1.10	2
12	Acetaminophen Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as	1.10	2
13	Acetaminophen Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as	1.10	2
14	Bumetanide	1.10	2
15	Vanillic Acid	1.10	2
16	isorhamnetin-3-O-beta-D-glucopyranosyl-(1-3)-alpha-L-rhamnopyranosyl-(1-6)-beta-D-galactopyranoside [Supplementary Concept] from	1.10	2
17	Metolazone	1.10	2
18	Salicylic Acid	1.10	2
19	Catechin	0.69	1
20	Pueraria	0.69	1
21	Kaempferols	0.69	1
22	Luteolin 5,7,3',4'-tetrahydroxy-flavone,	0.69	1
23	Kaempferols	0.69	1
24	Quercetin	0.69	1
25	Resveratrol	0.69	1
26	Bortezomib	0.69	1
27	d609	0.69	1
28	Famotidine	0.69	1
29	Hesperidin	0.69	1
30	Levodopa	0.69	1
31	Mafenide	0.69	1
32	4-Hydroxybenzoate-3-Monooxygenase	0.69	1
33	stx64	0.69	1
34	Sulpiride	0.69	1
35	alphitonin [Supplementary Concept] from	0.69	1
36	tiliroside	0.69	1

About CA12 as a Drug Target

CA12 (carbonic anhydrase 12) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 36 compounds with documented CA12 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

CA12 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.