CA14
MOLECULAR TARGETcarbonic anhydrase 14
CA14 (carbonic anhydrase 14) is targeted by 23 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting CA14
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Zonisamide | 2.40 | 10 |
| 2 | Indapamide | 1.95 | 6 |
| 3 | Chlorthalidone | 1.79 | 5 |
| 4 | Histamine | 1.79 | 5 |
| 5 | Sulfanilamide | 1.61 | 4 |
| 6 | benzolamide | 1.39 | 3 |
| 7 | Furosemide | 1.39 | 3 |
| 8 | caffeic acid | 1.10 | 2 |
| 9 | Histidine | 1.10 | 2 |
| 10 | Bumetanide | 1.10 | 2 |
| 11 | Celecoxib | 1.10 | 2 |
| 12 | Vanillic Acid | 1.10 | 2 |
| 13 | Mafenide | 1.10 | 2 |
| 14 | Metolazone | 1.10 | 2 |
| 15 | stx64 | 1.10 | 2 |
| 16 | Quercetin | 0.69 | 1 |
| 17 | Resveratrol | 0.69 | 1 |
| 18 | Spermidine | 0.69 | 1 |
| 19 | Bortezomib | 0.69 | 1 |
| 20 | Famotidine | 0.69 | 1 |
| 21 | Lacosamide | 0.69 | 1 |
| 22 | 4-Hydroxybenzoate-3-Monooxygenase | 0.69 | 1 |
| 23 | Spermine | 0.69 | 1 |
About CA14 as a Drug Target
CA14 (carbonic anhydrase 14) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 23 compounds with documented CA14 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
CA14 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.