What compounds target CA5B?

BiohacksAI has identified 34 compounds that interact with CA5B (carbonic anhydrase 5B). Top compounds include: Zonisamide, Indapamide, Chlorthalidone, Sulfanilamide, benzolamide. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is CA5B (carbonic anhydrase 5B)?

CA5B is carbonic anhydrase 5B. It is a molecular target for 34 compounds documented in PubMed bioassay data. UniProt ID: Q9Y2D0. NCBI Gene ID: 11238.

CA5B

MOLECULAR TARGET

carbonic anhydrase 5B

UniProt: Q9Y2D0 NCBI Gene: 1123834 compounds

CA5B (carbonic anhydrase 5B) is targeted by 34 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting CA5B

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	Zonisamide	2.40	10
2	Indapamide	1.95	6
3	Chlorthalidone	1.61	4
4	Sulfanilamide	1.61	4
5	benzolamide	1.39	3
6	Furosemide	1.39	3
7	Histamine	1.39	3
8	Histidine	1.10	2
9	Bumetanide	1.10	2
10	Celecoxib	1.10	2
11	Metolazone	1.10	2
12	stx64	1.10	2
13	Tryptophan	1.10	2
14	caffeic acid	0.69	1
15	Catechin	0.69	1
16	Tyrosine	0.69	1
17	Resveratrol	0.69	1
18	Spermidine	0.69	1
19	Tyrosine	0.69	1
20	Bortezomib	0.69	1
21	Famotidine	0.69	1
22	Hydrochloric Acid	0.69	1
23	Hydrogen Cyanide Hydrogen cyanide (HCN);	0.69	1
24	hydrogen iodide	0.69	1
25	Hydrogen Sulfide	0.69	1
26	Hydrogen Sulfide	0.69	1
27	Lacosamide	0.69	1
28	Levodopa	0.69	1
29	Nitric Acid Nitric acid (HNO3).	0.69	1
30	Sildenafil Citrate	0.69	1
31	Spermine	0.69	1
32	Sulfides Chemical groups containing	0.69	1
33	Sulpiride	0.69	1
34	tyrosol	0.69	1

About CA5B as a Drug Target

CA5B (carbonic anhydrase 5B) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 34 compounds with documented CA5B interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

CA5B inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.