What compounds target CASP7?

BiohacksAI has identified 33 compounds that interact with CASP7 (caspase 7). Top compounds include: Disulfiram, Astemizole Antihistamine drug now withdrawn from, Dactinomycin, Celecoxib, Lovastatin. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is CASP7 (caspase 7)?

CASP7 is caspase 7. It is a molecular target for 33 compounds documented in PubMed bioassay data. UniProt ID: AAP35329. NCBI Gene ID: 840.

CASP7

MOLECULAR TARGET

caspase 7

UniProt: AAP35329 NCBI Gene: 84033 compounds

CASP7 (caspase 7) is targeted by 33 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting CASP7

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	Disulfiram	1.79	5
2	Astemizole Antihistamine drug now withdrawn from	1.61	4
3	Dactinomycin	1.61	4
4	Celecoxib	1.39	3
5	Lovastatin	1.39	3
6	Aprepitant	1.10	2
7	Bortezomib	1.10	2
8	Daunorubicin	1.10	2
9	Ethinyl Estradiol	1.10	2
10	Methylcholanthrene	1.10	2
11	o-Phthalaldehyde	1.10	2
12	Potassium Dichromate Chromic acid (H2Cr2O7), dipotassium salt.	1.10	2
13	Thioridazine	1.10	2
14	Atorvastatin	0.69	1
15	myricetin-3-O-galactopyranoside [Supplementary Concept]	0.69	1
16	Cetylpyridinium Cationic bactericidal surfactant used as	0.69	1
17	Dasatinib	0.69	1
18	Isopentenyladenosine N(6)-[delta(3)-isopentenyl]adenosine. Isopentenyl derivative of adenosine which is	0.69	1
19	Lithocholic Acid	0.69	1
20	Lumefantrine	0.69	1
21	Maprotiline	0.69	1
22	Melphalan	0.69	1
23	Mometasone Furoate	0.69	1
24	ninhydrin	0.69	1
25	Nocodazole Nocodazole is	0.69	1
26	oxatomide [Supplementary Concept] structure;	0.69	1
27	Oxymetholone	0.69	1
28	Perphenazine	0.69	1
29	Promethazine	0.69	1
30	Reserpine	0.69	1
31	Retinaldehyde	0.69	1
32	Safrole	0.69	1
33	triflupromazine hydrochloride	0.69	1

About CASP7 as a Drug Target

CASP7 (caspase 7) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 33 compounds with documented CASP7 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

CASP7 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.