CDK11B
MOLECULAR TARGETcyclin dependent kinase 11B
CDK11B (cyclin dependent kinase 11B) is targeted by 14 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting CDK11B
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | foretinib | 4.34 | 76 |
| 2 | tozasertib | 4.33 | 75 |
| 3 | molibresib | 3.81 | 44 |
| 4 | pazopanib | 3.69 | 39 |
| 5 | bms 387032 | 3.47 | 31 |
| 6 | linifanib | 3.33 | 27 |
| 7 | at 7519 | 3.33 | 27 |
| 8 | jnj 7706621 | 3.09 | 21 |
| 9 | defosbarasertib | 2.89 | 17 |
| 10 | bms 345541 | 2.71 | 14 |
| 11 | ast 487 | 2.56 | 12 |
| 12 | rg 547 | 2.08 | 7 |
| 13 | Crizotinib | 0.69 | 1 |
| 14 | indirubin | 0.69 | 1 |
About CDK11B as a Drug Target
CDK11B (cyclin dependent kinase 11B) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 14 compounds with documented CDK11B interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
CDK11B inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.