CHRNA1
MOLECULAR TARGETcholinergic receptor nicotinic alpha 1 subunit
CHRNA1 (cholinergic receptor nicotinic alpha 1 subunit) is targeted by 8 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting CHRNA1
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | epibatidine | 4.20 | 66 |
| 2 | molibresib | 3.81 | 44 |
| 3 | gsk046 | 2.40 | 10 |
| 4 | gsk778 | 2.08 | 7 |
| 5 | desnitroimidacloprid | 1.95 | 6 |
| 6 | Nicotine Nicotine is highly toxic alkaloid. It is | 1.61 | 4 |
| 7 | Mecamylamine | 0.69 | 1 |
| 8 | Pancuronium | 0.69 | 1 |
About CHRNA1 as a Drug Target
CHRNA1 (cholinergic receptor nicotinic alpha 1 subunit) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 8 compounds with documented CHRNA1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
CHRNA1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.