COQ8A
MOLECULAR TARGETcoenzyme Q8A
COQ8A (coenzyme Q8A) is targeted by 14 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting COQ8A
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | erlotinib | 5.55 | 256 |
| 2 | vandetanib | 4.30 | 73 |
| 3 | canertinib | 3.53 | 33 |
| 4 | tae 684 | 3.43 | 30 |
| 5 | fedratinib | 3.40 | 29 |
| 6 | saracatinib | 3.33 | 27 |
| 7 | jnj 7706621 | 3.09 | 21 |
| 8 | galunisertib | 2.94 | 18 |
| 9 | r 406 | 2.83 | 16 |
| 10 | milciclib | 2.77 | 15 |
| 11 | cyc 116 | 2.08 | 7 |
| 12 | tg100 115 | 2.08 | 7 |
| 13 | osi 632 | 1.79 | 5 |
| 14 | Dasatinib | 0.69 | 1 |
About COQ8A as a Drug Target
COQ8A (coenzyme Q8A) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 14 compounds with documented COQ8A interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
COQ8A inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.