CYCLIN-DEPENDENT
MOLECULAR TARGETCyclin-dependent kinase 2 (human)
CYCLIN-DEPENDENT (Cyclin-dependent kinase 2 (human)) is targeted by 11 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting CYCLIN-DEPENDENT
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Dichlororibofuranosylbenzimidazole | 3.64 | 37 |
| 2 | Sorafenib | 3.22 | 24 |
| 3 | indirubin | 2.83 | 16 |
| 4 | kenpaullone | 2.40 | 10 |
| 5 | Harmine Alkaloid isolated from seeds of PEGANUM HARMALA; ZYGOPHYLLACEAE. It is identical to banisterine, or telepathine, from Banisteria caapi and is | 1.95 | 6 |
| 6 | alsterpaullone | 1.79 | 5 |
| 7 | hydroxyfasudil [Supplementary Concept] | 1.39 | 3 |
| 8 | sp600125 | 1.10 | 2 |
| 9 | Adenosine Triphosphate | 0.69 | 1 |
| 10 | Crizotinib | 0.69 | 1 |
| 11 | ha1004 | 0.69 | 1 |
About CYCLIN-DEPENDENT as a Drug Target
CYCLIN-DEPENDENT (Cyclin-dependent kinase 2 (human)) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 11 compounds with documented CYCLIN-DEPENDENT interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
CYCLIN-DEPENDENT inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.