DAPK1
MOLECULAR TARGETdeath associated protein kinase 1
DAPK1 (death associated protein kinase 1) is targeted by 21 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting DAPK1
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | morin | 4.28 | 71 |
| 2 | ruxolitinib | 4.23 | 68 |
| 3 | pi 103 | 4.17 | 64 |
| 4 | bi 2536 | 4.01 | 54 |
| 5 | midostaurin | 3.85 | 46 |
| 6 | tae 684 | 3.43 | 30 |
| 7 | fedratinib | 3.40 | 29 |
| 8 | sulfuretin | 3.14 | 22 |
| 9 | athraquinones a | 3.14 | 22 |
| 10 | lestaurtinib | 3.04 | 20 |
| 11 | ruboxistaurin | 2.94 | 18 |
| 12 | r 406 | 2.83 | 16 |
| 13 | gossypetin | 2.83 | 16 |
| 14 | kw 2449 | 2.64 | 13 |
| 15 | gsk 690693 | 2.64 | 13 |
| 16 | purpurin | 2.64 | 13 |
| 17 | gsk 461364 | 2.40 | 10 |
| 18 | su 014813 | 2.20 | 8 |
| 19 | Kaempferols | 0.69 | 1 |
| 20 | Quercetin | 0.69 | 1 |
| 21 | pictilisib | 0.69 | 1 |
About DAPK1 as a Drug Target
DAPK1 (death associated protein kinase 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 21 compounds with documented DAPK1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
DAPK1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.