DAPK3
MOLECULAR TARGETdeath associated protein kinase 3
DAPK3 (death associated protein kinase 3) is targeted by 28 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting DAPK3
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | gefitinib | 5.67 | 290 |
| 2 | erlotinib | 5.55 | 256 |
| 3 | foretinib | 4.34 | 76 |
| 4 | tozasertib | 4.33 | 75 |
| 5 | ruxolitinib | 4.23 | 68 |
| 6 | pi 103 | 4.17 | 64 |
| 7 | bi 2536 | 4.01 | 54 |
| 8 | midostaurin | 3.85 | 46 |
| 9 | silmitasertib | 3.78 | 43 |
| 10 | nintedanib | 3.61 | 36 |
| 11 | pelitinib | 3.50 | 32 |
| 12 | tae 684 | 3.43 | 30 |
| 13 | fedratinib | 3.40 | 29 |
| 14 | sp 600125 | 3.22 | 24 |
| 15 | sulfuretin | 3.14 | 22 |
| 16 | dovitinib | 3.09 | 21 |
| 17 | jnj 7706621 | 3.09 | 21 |
| 18 | lestaurtinib | 3.04 | 20 |
| 19 | ruboxistaurin | 2.94 | 18 |
| 20 | r 406 | 2.83 | 16 |
| 21 | kw 2449 | 2.64 | 13 |
| 22 | gsk 690693 | 2.64 | 13 |
| 23 | ast 487 | 2.56 | 12 |
| 24 | gsk 461364 | 2.40 | 10 |
| 25 | su 014813 | 2.20 | 8 |
| 26 | sp600125 | 1.39 | 3 |
| 27 | hydroxyfasudil [Supplementary Concept] | 1.10 | 2 |
| 28 | pictilisib | 0.69 | 1 |
About DAPK3 as a Drug Target
DAPK3 (death associated protein kinase 3) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 28 compounds with documented DAPK3 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
DAPK3 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.