EPHA8
MOLECULAR TARGETEPH receptor A8
EPHA8 (EPH receptor A8) is targeted by 23 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting EPHA8
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | gefitinib | 5.67 | 290 |
| 2 | erlotinib | 5.55 | 256 |
| 3 | imatinib | 5.47 | 236 |
| 4 | foretinib | 4.34 | 76 |
| 5 | tozasertib | 4.33 | 75 |
| 6 | vandetanib | 4.30 | 73 |
| 7 | nilotinib | 4.17 | 64 |
| 8 | bosutinib | 4.08 | 58 |
| 9 | doramapimod | 4.06 | 57 |
| 10 | canertinib | 3.53 | 33 |
| 11 | pelitinib | 3.50 | 32 |
| 12 | fedratinib | 3.40 | 29 |
| 13 | neflamapimod | 3.30 | 26 |
| 14 | dasatinib anhydrous | 3.09 | 21 |
| 15 | r 406 | 2.83 | 16 |
| 16 | cediranib | 2.83 | 16 |
| 17 | masitinib | 2.77 | 15 |
| 18 | pha 665752 | 2.71 | 14 |
| 19 | ast 487 | 2.56 | 12 |
| 20 | raf 265 | 2.48 | 11 |
| 21 | Sorafenib | 1.95 | 6 |
| 22 | Crizotinib | 0.69 | 1 |
| 23 | Dasatinib | 0.69 | 1 |
About EPHA8 as a Drug Target
EPHA8 (EPH receptor A8) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 23 compounds with documented EPHA8 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
EPHA8 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.