F12
MOLECULAR TARGETcoagulation factor XII
F12 (coagulation factor XII) is targeted by 4 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting F12
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | benzamidine | 3.04 | 20 |
| 2 | nafamostat | 3.00 | 19 |
| 3 | Bortezomib | 0.69 | 1 |
| 4 | Gabexate | 0.69 | 1 |
About F12 as a Drug Target
F12 (coagulation factor XII) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 4 compounds with documented F12 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
F12 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.