FGFR4
MOLECULAR TARGETfibroblast growth factor receptor 4
FGFR4 (fibroblast growth factor receptor 4) is targeted by 33 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting FGFR4
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | tozasertib | 4.33 | 75 |
| 2 | vandetanib | 4.30 | 73 |
| 3 | ponatinib | 4.26 | 70 |
| 4 | ceritinib | 4.19 | 65 |
| 5 | doramapimod | 4.06 | 57 |
| 6 | brigatinib | 3.81 | 44 |
| 7 | pazopanib | 3.69 | 39 |
| 8 | nintedanib | 3.61 | 36 |
| 9 | tae 684 | 3.43 | 30 |
| 10 | fedratinib | 3.40 | 29 |
| 11 | fexagratinib | 3.33 | 27 |
| 12 | dovitinib | 3.09 | 21 |
| 13 | lestaurtinib | 3.04 | 20 |
| 14 | lenvatinib | 3.04 | 20 |
| 15 | r 406 | 2.83 | 16 |
| 16 | cediranib | 2.83 | 16 |
| 17 | pd 173074 | 2.83 | 16 |
| 18 | infigratinib | 2.77 | 15 |
| 19 | erdafitinib | 2.77 | 15 |
| 20 | kw 2449 | 2.64 | 13 |
| 21 | ast 487 | 2.56 | 12 |
| 22 | ly 2874455 | 2.56 | 12 |
| 23 | motesanib | 2.48 | 11 |
| 24 | brivanib | 2.48 | 11 |
| 25 | pemigatinib | 2.40 | 10 |
| 26 | su 014813 | 2.20 | 8 |
| 27 | rebastinib | 2.20 | 8 |
| 28 | futibatinib | 2.20 | 8 |
| 29 | fisogatinib | 2.20 | 8 |
| 30 | h3b 6527 | 1.95 | 6 |
| 31 | osi 632 | 1.79 | 5 |
| 32 | fgfr inhibitor debio 1347 | 1.79 | 5 |
| 33 | Acrylamide | 0.69 | 1 |
About FGFR4 as a Drug Target
FGFR4 (fibroblast growth factor receptor 4) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 33 compounds with documented FGFR4 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
FGFR4 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.