FKBP5
MOLECULAR TARGETFKBP prolyl isomerase 5
FKBP5 (FKBP prolyl isomerase 5) is targeted by 6 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting FKBP5
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | sirolimus | 4.82 | 123 |
| 2 | tacrolimus anhydrous | 4.45 | 85 |
| 3 | gpi 1046 | 2.20 | 8 |
| 4 | Sirolimus | 1.39 | 3 |
| 5 | Everolimus | 0.69 | 1 |
| 6 | bdb chembl4090599 | 0.69 | 1 |
About FKBP5 as a Drug Target
FKBP5 (FKBP prolyl isomerase 5) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 6 compounds with documented FKBP5 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
FKBP5 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.