FLT3
MOLECULAR TARGETfms related receptor tyrosine kinase 3
FLT3 (fms related receptor tyrosine kinase 3) is targeted by 14 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting FLT3
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Sorafenib | 4.30 | 73 |
| 2 | Axitinib | 2.08 | 7 |
| 3 | Crizotinib | 2.08 | 7 |
| 4 | pictilisib | 1.95 | 6 |
| 5 | Afatinib | 1.39 | 3 |
| 6 | tyrphostin ag 1295 | 1.39 | 3 |
| 7 | Apigenin 5,7,4'-trihydroxy-flavone, | 0.69 | 1 |
| 8 | Kaempferols | 0.69 | 1 |
| 9 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | 0.69 | 1 |
| 10 | myricetin-3-O-galactopyranoside [Supplementary Concept] | 0.69 | 1 |
| 11 | Quercetin | 0.69 | 1 |
| 12 | kenpaullone | 0.69 | 1 |
| 13 | sp600125 | 0.69 | 1 |
| 14 | tyrphostin ag 1478 | 0.69 | 1 |
About FLT3 as a Drug Target
FLT3 (fms related receptor tyrosine kinase 3) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 14 compounds with documented FLT3 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
FLT3 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.