FOLR1
MOLECULAR TARGETfolate receptor alpha
FOLR1 (folate receptor alpha) is targeted by 7 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting FOLR1
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | methotrexate | 6.00 | 404 |
| 2 | raltitrexed | 3.58 | 35 |
| 3 | pralatrexate | 2.08 | 7 |
| 4 | Pemetrexed | 1.95 | 6 |
| 5 | Methotrexate | 1.61 | 4 |
| 6 | Folic Acid | 1.10 | 2 |
| 7 | bdb chembl4866304 | 0.69 | 1 |
About FOLR1 as a Drug Target
FOLR1 (folate receptor alpha) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 7 compounds with documented FOLR1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
FOLR1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.