FTO
MOLECULAR TARGETFTO alpha-ketoglutarate dependent dioxygenase
FTO (FTO alpha-ketoglutarate dependent dioxygenase) is targeted by 15 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting FTO
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | tacrine | 6.08 | 436 |
| 2 | morin | 4.28 | 71 |
| 3 | radicicol | 4.06 | 57 |
| 4 | amiloride | 3.95 | 51 |
| 5 | rhein | 3.58 | 35 |
| 6 | meclofenamic acid | 3.50 | 32 |
| 7 | n oxalylglycine | 3.43 | 30 |
| 8 | entacapone | 3.43 | 30 |
| 9 | roxadustat | 3.18 | 23 |
| 10 | fluorescein | 3.09 | 21 |
| 11 | diacerein | 2.77 | 15 |
| 12 | fenobam anhydrous | 2.64 | 13 |
| 13 | Demeclocycline | 0.69 | 1 |
| 14 | Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as | 0.69 | 1 |
| 15 | tyrphostin ag 1478 | 0.69 | 1 |
About FTO as a Drug Target
FTO (FTO alpha-ketoglutarate dependent dioxygenase) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 15 compounds with documented FTO interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
FTO inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.