GPT2
MOLECULAR TARGETglutamic--pyruvic transaminase 2
GPT2 (glutamic--pyruvic transaminase 2) is targeted by 17 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting GPT2
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Disulfiram | 1.61 | 4 |
| 2 | Epinephrine | 1.61 | 4 |
| 3 | Methyldopa | 1.61 | 4 |
| 4 | Norepinephrine Precursor of epinephrine that is secreted by | 1.61 | 4 |
| 5 | 5-Hydroxytryptophan | 1.10 | 2 |
| 6 | Duloxetine Hydrochloride | 1.10 | 2 |
| 7 | Kaempferols | 1.10 | 2 |
| 8 | Quercetin | 1.10 | 2 |
| 9 | 5-Hydroxytryptophan | 1.10 | 2 |
| 10 | Benzydamine | 1.10 | 2 |
| 11 | Carbaryl | 1.10 | 2 |
| 12 | Catechin | 1.10 | 2 |
| 13 | Isoproterenol Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on | 1.10 | 2 |
| 14 | Nitrofurazone | 1.10 | 2 |
| 15 | piceatannol | 1.10 | 2 |
| 16 | Promethazine | 1.10 | 2 |
| 17 | skf83959 | 1.10 | 2 |
About GPT2 as a Drug Target
GPT2 (glutamic--pyruvic transaminase 2) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 17 compounds with documented GPT2 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
GPT2 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.