GSK3B
MOLECULAR TARGETglycogen synthase kinase 3 beta
GSK3B (glycogen synthase kinase 3 beta) is targeted by 19 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting GSK3B
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | alsterpaullone | 3.04 | 20 |
| 2 | kenpaullone | 2.83 | 16 |
| 3 | indirubin | 1.95 | 6 |
| 4 | Apigenin 5,7,4'-trihydroxy-flavone, | 1.61 | 4 |
| 5 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | 1.61 | 4 |
| 6 | Kaempferols | 1.39 | 3 |
| 7 | Quercetin | 1.39 | 3 |
| 8 | Harmine Alkaloid isolated from seeds of PEGANUM HARMALA; ZYGOPHYLLACEAE. It is identical to banisterine, or telepathine, from Banisteria caapi and is | 1.39 | 3 |
| 9 | Lithium Chloride | 1.39 | 3 |
| 10 | chrysin | 1.10 | 2 |
| 11 | fisetin | 1.10 | 2 |
| 12 | ly294002 | 1.10 | 2 |
| 13 | Sorafenib | 1.10 | 2 |
| 14 | egcg | 0.69 | 1 |
| 15 | Rutin | 0.69 | 1 |
| 16 | Ursolic Acid | 0.69 | 1 |
| 17 | Oleanolic Acid | 0.69 | 1 |
| 18 | sp600125 | 0.69 | 1 |
| 19 | Zearalenone (S-(E))-3,4,5,6,8,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradec in-1,7(8H)-dione. | 0.69 | 1 |
About GSK3B as a Drug Target
GSK3B (glycogen synthase kinase 3 beta) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 19 compounds with documented GSK3B interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
GSK3B inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.