HRH4
MOLECULAR TARGEThistamine receptor H4
HRH4 (histamine receptor H4) is targeted by 9 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting HRH4
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Histamine | 4.36 | 77 |
| 2 | Dimaprit | 2.30 | 9 |
| 3 | Impromidine | 1.95 | 6 |
| 4 | Burimamide | 1.61 | 4 |
| 5 | Loxapine | 1.39 | 3 |
| 6 | Amoxapine | 0.69 | 1 |
| 7 | Astemizole Antihistamine drug now withdrawn from | 0.69 | 1 |
| 8 | Metergoline | 0.69 | 1 |
| 9 | Pramipexole | 0.69 | 1 |
About HRH4 as a Drug Target
HRH4 (histamine receptor H4) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 9 compounds with documented HRH4 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
HRH4 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.