HSP90B1
MOLECULAR TARGETheat shock protein 90 beta family member 1
HSP90B1 (heat shock protein 90 beta family member 1) is targeted by 11 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting HSP90B1
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | neca | 4.86 | 128 |
| 2 | molibresib | 3.81 | 44 |
| 3 | luminespib | 3.58 | 35 |
| 4 | biib021 | 3.04 | 20 |
| 5 | pu h71 | 2.89 | 17 |
| 6 | onalespib | 2.89 | 17 |
| 7 | snx 2112 | 2.77 | 15 |
| 8 | ganetespib | 2.71 | 14 |
| 9 | 2-Chloroadenosine 2-Chloroadenosine. | 1.10 | 2 |
| 10 | Adenosine Diphosphate Adenosine 5'-(trihydrogen diphosphate). | 0.69 | 1 |
| 11 | Adenosine Triphosphate | 0.69 | 1 |
About HSP90B1 as a Drug Target
HSP90B1 (heat shock protein 90 beta family member 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 11 compounds with documented HSP90B1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
HSP90B1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.