IKBKB
MOLECULAR TARGETinhibitor of nuclear factor kappa B kinase subunit beta
IKBKB (inhibitor of nuclear factor kappa B kinase subunit beta) is targeted by 21 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting IKBKB
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | ruxolitinib | 4.23 | 68 |
| 2 | midostaurin | 3.85 | 46 |
| 3 | gambogic acid | 3.69 | 39 |
| 4 | fedratinib | 3.40 | 29 |
| 5 | 78 dihydroxyflavone | 3.14 | 22 |
| 6 | diosmin | 3.09 | 21 |
| 7 | lestaurtinib | 3.04 | 20 |
| 8 | r 406 | 2.83 | 16 |
| 9 | imd 0354 | 2.83 | 16 |
| 10 | bms 345541 | 2.71 | 14 |
| 11 | kw 2449 | 2.64 | 13 |
| 12 | ast 487 | 2.56 | 12 |
| 13 | as 602868 | 2.56 | 12 |
| 14 | ertiprotafib | 2.56 | 12 |
| 15 | su 014813 | 2.20 | 8 |
| 16 | gsk 625137a | 1.79 | 5 |
| 17 | alsterpaullone | 0.69 | 1 |
| 18 | Aurintricarboxylic Acid | 0.69 | 1 |
| 19 | chicoric acid | 0.69 | 1 |
| 20 | Crizotinib | 0.69 | 1 |
| 21 | sp600125 | 0.69 | 1 |
About IKBKB as a Drug Target
IKBKB (inhibitor of nuclear factor kappa B kinase subunit beta) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 21 compounds with documented IKBKB interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
IKBKB inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.