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BiohacksAI

Evidence-Based Biohacking

Patent Pending

IRAK3

MOLECULAR TARGET

interleukin 1 receptor associated kinase 3

UniProt: Q9Y616NCBI Gene: 1121336 compounds

IRAK3 (interleukin 1 receptor associated kinase 3) is targeted by 36 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting IRAK3

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#CompoundConfidenceActive Assays
1gefitinib5.67290
2foretinib4.3476
3tozasertib4.3375
4midostaurin3.8546
5pazopanib3.6939
6nintedanib3.6136
7canertinib3.5333
8bms 3870323.4731
9tae 6843.4330
10fedratinib3.4029
11gilteritinib3.4029
12mln 80543.3327
13sgi 17763.2625
14tandutinib3.2224
15omipalisib3.1422
16jnj 77066213.0921
17lestaurtinib3.0420
18pacritinib3.0420
19defosbarasertib2.8917
20r 4062.8316
21k 252a2.8316
22milciclib2.7715
23pha 6657522.7114
24crenolanib2.7114
25azd 54382.7114
26kw 24492.6413
27zotiraciclib2.5612
28mk 51082.4811
29gsk 4613642.4010
30su 0148132.208
31cyc 1162.087
32mk 24612.087
33fostamatinib2.087
34gsk 10596151.956
35Crizotinib1.102
36pictilisib0.691

About IRAK3 as a Drug Target

IRAK3 (interleukin 1 receptor associated kinase 3) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 36 compounds with documented IRAK3 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

IRAK3 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.