KARS1
MOLECULAR TARGETlysyl-tRNA synthetase 1
KARS1 (lysyl-tRNA synthetase 1) is targeted by 3 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting KARS1
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | imatinib | 5.47 | 236 |
| 2 | tae 684 | 3.43 | 30 |
| 3 | methyl 13-(alpha-naphthalene)aminodeisopropyldehydroabietate [Supplementary Concept] | 0.69 | 1 |
About KARS1 as a Drug Target
KARS1 (lysyl-tRNA synthetase 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 3 compounds with documented KARS1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
KARS1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.