Question 1

What compounds target KMT2A?

Accepted Answer

BiohacksAI has identified 6 compounds that interact with KMT2A (lysine methyltransferase 2A). Top compounds include: s adenosylhomocysteine, Tannins Polyphenolic compounds with molecular weights of around 500-3000 daltons and containing enough hydroxyl groups (1-2 per 100 MW) for effective cross linking of other compounds (ASTRINGENTS)., Aurintricarboxylic Acid, Nitroblue Tetrazolium Colorless to yellow dye that is reducible to blue or black formazan crystals by certain cells; formerly used to distinguish between nonbacterial and bacterial diseases,, scutellarein. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

Question 2

What is KMT2A (lysine methyltransferase 2A)?

Accepted Answer

KMT2A is lysine methyltransferase 2A. It is a molecular target for 6 compounds documented in PubMed bioassay data. UniProt ID: Q03164. NCBI Gene ID: 4297.

#	Compound	Confidence	Active Assays
1	s adenosylhomocysteine	1.10	2
2	Tannins Polyphenolic compounds with molecular weights of around 500-3000 daltons and containing enough hydroxyl groups (1-2 per 100 MW) for effective cross linking of other compounds (ASTRINGENTS).	0.69	1
3	Aurintricarboxylic Acid	0.69	1
4	Nitroblue Tetrazolium Colorless to yellow dye that is reducible to blue or black formazan crystals by certain cells; formerly used to distinguish between nonbacterial and bacterial diseases,	0.69	1
5	scutellarein	0.69	1
6	Suramin	0.69	1

BiohacksAI

KMT2A

Compounds Targeting KMT2A

About KMT2A as a Drug Target