MAP3K5
MOLECULAR TARGETmitogen-activated protein kinase kinase kinase 5
MAP3K5 (mitogen-activated protein kinase kinase kinase 5) is targeted by 12 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting MAP3K5
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | at 9283 | 3.09 | 21 |
| 2 | lestaurtinib | 3.04 | 20 |
| 3 | hymenialdisine | 3.00 | 19 |
| 4 | k 252a | 2.83 | 16 |
| 5 | mli 2 | 2.64 | 13 |
| 6 | selonsertib | 2.48 | 11 |
| 7 | y 39983 | 2.20 | 8 |
| 8 | amg 900 | 2.08 | 7 |
| 9 | pf 03814735 | 1.79 | 5 |
| 10 | fisetin | 0.69 | 1 |
| 11 | Quercetin | 0.69 | 1 |
| 12 | sp600125 | 0.69 | 1 |
About MAP3K5 as a Drug Target
MAP3K5 (mitogen-activated protein kinase kinase kinase 5) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 12 compounds with documented MAP3K5 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
MAP3K5 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.