MC5R
MOLECULAR TARGETmelanocortin 5 receptor
MC5R (melanocortin 5 receptor) is targeted by 14 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting MC5R
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | paclitaxel | 7.17 | 1301 |
| 2 | tamoxifen | 5.88 | 358 |
| 3 | amiodarone | 4.51 | 90 |
| 4 | afamelanotide | 4.04 | 56 |
| 5 | intermedine | 3.95 | 51 |
| 6 | fluphenazine | 3.91 | 49 |
| 7 | ciglitazone | 3.81 | 44 |
| 8 | melatonan | 3.53 | 33 |
| 9 | alpha-MSH | 3.43 | 30 |
| 10 | cetylpyridinium bromide | 2.20 | 8 |
| 11 | benzothiazyl disulfide | 1.95 | 6 |
| 12 | setmelanotide | 1.95 | 6 |
| 13 | bremelanotide [Supplementary Concept] | 1.61 | 4 |
| 14 | melanotan-II [Supplementary Concept] synthetic cyclic heptapeptide, | 0.69 | 1 |
About MC5R as a Drug Target
MC5R (melanocortin 5 receptor) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 14 compounds with documented MC5R interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
MC5R inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.