What compounds target MINK1?

BiohacksAI has identified 39 compounds that interact with MINK1 (misshapen like kinase 1). Top compounds include: gefitinib, erlotinib, alvocidib, foretinib, tozasertib. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is MINK1 (misshapen like kinase)?

MINK1 is misshapen like kinase 1. It is a molecular target for 39 compounds documented in PubMed bioassay data. NCBI Gene ID: 50488.

MINK1

MOLECULAR TARGET

misshapen like kinase 1

NCBI Gene: 5048839 compounds

MINK1 (misshapen like kinase 1) is targeted by 39 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting MINK1

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	gefitinib	5.67	290
2	erlotinib	5.55	256
3	alvocidib	4.52	91
4	foretinib	4.34	76
5	tozasertib	4.33	75
6	vandetanib	4.30	73
7	bosutinib	4.08	58
8	doramapimod	4.06	57
9	bi 2536	4.01	54
10	quizartinib	3.99	53
11	midostaurin	3.85	46
12	neratinib	3.66	38
13	nintedanib	3.61	36
14	canertinib	3.53	33
15	tae 684	3.43	30
16	fedratinib	3.40	29
17	dovitinib	3.09	21
18	lestaurtinib	3.04	20
19	ruboxistaurin	2.94	18
20	galunisertib	2.94	18
21	cediranib	2.83	16
22	sotrastaurin	2.77	15
23	pha 665752	2.71	14
24	plx 4720	2.71	14
25	kw 2449	2.64	13
26	ast 487	2.56	12
27	brivanib	2.48	11
28	su 014813	2.20	8
29	rebastinib	2.20	8
30	mubritinib	2.20	8
31	cyc 116	2.08	7
32	enzastaurin	2.08	7
33	pf 03814735	1.79	5
34	alsterpaullone	0.69	1
35	Axitinib	0.69	1
36	Crizotinib	0.69	1
37	Dasatinib	0.69	1
38	Sorafenib	0.69	1
39	sp600125	0.69	1

About MINK1 as a Drug Target

MINK1 (misshapen like kinase 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 39 compounds with documented MINK1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

MINK1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.