What compounds target MITF?

BiohacksAI has identified 45 compounds that interact with MITF (melanocyte inducing transcription factor). Top compounds include: Cefdinir, Ethidium, Oxytetracycline, egcg, colchine. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is MITF (melanocyte inducing transcription)?

MITF is melanocyte inducing transcription factor. It is a molecular target for 45 compounds documented in PubMed bioassay data. UniProt ID: O75030. NCBI Gene ID: 4286.

MITF

MOLECULAR TARGET

melanocyte inducing transcription factor

UniProt: O75030 NCBI Gene: 428645 compounds

MITF (melanocyte inducing transcription factor) is targeted by 45 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting MITF

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	Cefdinir	1.95	6
2	Ethidium	1.79	5
3	Oxytetracycline	1.79	5
4	egcg	1.61	4
5	colchine	1.61	4
6	Anthralin	1.39	3
7	Aurintricarboxylic Acid	1.39	3
8	Biotin	1.39	3
9	Rolitetracycline	1.39	3
10	myricetin-3-O-galactopyranoside [Supplementary Concept]	1.10	2
11	Rutin	1.10	2
12	cycloheximide	1.10	2
13	Oxyphenbutazone	1.10	2
14	Topotecan	1.10	2
15	Methylene Blue	0.69	1
16	Rosmarinic Acid	0.69	1
17	Anisomycin	0.69	1
18	Astemizole Antihistamine drug now withdrawn from	0.69	1
19	Azacitidine	0.69	1
20	Azacitidine	0.69	1
21	Bortezomib	0.69	1
22	Calcimycin	0.69	1
23	Camptothecin	0.69	1
24	Carmine Coloring matter from	0.69	1
25	celastrol	0.69	1
26	Ciclopirox	0.69	1
27	clofilium tosylate	0.69	1
28	Demecolcine	0.69	1
29	Digitoxigenin 3 beta,14-Dihydroxy-5 beta-card-20(22)enolide.	0.69	1
30	Digoxigenin 3 beta,12 beta,14-Trihydroxy-5 beta-card-20(22)-enolide.	0.69	1
31	Digoxin	0.69	1
32	Droxidopa	0.69	1
33	juglone hydroxylase [Supplementary Concept] catalyzes	0.69	1
34	Lanatosides Glycosides from DIGITALIS lanata leaf. Lanatoside C has actions similar to DIGOXIN. Mixtures of lanatosides A, B, and C have also been used. (From Martindale,	0.69	1
35	Levodopa	0.69	1
36	Niclosamide	0.69	1
37	Nocodazole Nocodazole is	0.69	1
38	pictilisib	0.69	1
39	Podophyllotoxin	0.69	1
40	Strophanthidin 3 beta,5,14-Trihydroxy-19-oxo-5 beta-card-20(22)-enolide.	0.69	1
41	torin 1	0.69	1
42	tyrphostin 9	0.69	1
43	vinblastine sulfate	0.69	1
44	Vincristine	0.69	1
45	Vorinostat	0.69	1

About MITF as a Drug Target

MITF (melanocyte inducing transcription factor) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 45 compounds with documented MITF interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

MITF inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.