NAPRT
MOLECULAR TARGETnicotinate phosphoribosyltransferase
NAPRT (nicotinate phosphoribosyltransferase) is targeted by 11 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting NAPRT
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | flufenamic acid | 4.14 | 62 |
| 2 | benzoic acid | 4.11 | 60 |
| 3 | mefenamic acid | 3.93 | 50 |
| 4 | 2 picolinic acid | 2.83 | 16 |
| 5 | Salicylic Acid | 1.10 | 2 |
| 6 | Aminopyrine | 0.69 | 1 |
| 7 | Antipyrine | 0.69 | 1 |
| 8 | Oxyphenbutazone | 0.69 | 1 |
| 9 | Phenylbutazone | 0.69 | 1 |
| 10 | Picloram | 0.69 | 1 |
| 11 | Sulfinpyrazone | 0.69 | 1 |
About NAPRT as a Drug Target
NAPRT (nicotinate phosphoribosyltransferase) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 11 compounds with documented NAPRT interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
NAPRT inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.