NPC1L1
MOLECULAR TARGETNPC1 like intracellular cholesterol transporter 1
NPC1L1 (NPC1 like intracellular cholesterol transporter 1) is targeted by 3 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting NPC1L1
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | 7 oxocholesterol | 2.30 | 9 |
| 2 | Ezetimibe | 1.79 | 5 |
| 3 | Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as | 1.61 | 4 |
About NPC1L1 as a Drug Target
NPC1L1 (NPC1 like intracellular cholesterol transporter 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 3 compounds with documented NPC1L1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
NPC1L1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.