NR1H3
MOLECULAR TARGETnuclear receptor subfamily 1 group H member 3
NR1H3 (nuclear receptor subfamily 1 group H member 3) is targeted by 16 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting NR1H3
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | t091317 | 4.47 | 86 |
| 2 | alitretinoin | 4.03 | 55 |
| 3 | bexarotene | 4.03 | 55 |
| 4 | 22r hydroxycholesterol | 2.77 | 15 |
| 5 | cyanidin | 2.40 | 10 |
| 6 | tryprostatin a | 2.30 | 9 |
| 7 | lxr 623 | 1.95 | 6 |
| 8 | 24s25 epoxycholesterol | 1.95 | 6 |
| 9 | gsk 4112 | 1.79 | 5 |
| 10 | Hesperidin | 1.39 | 3 |
| 11 | Desmosterol | 1.10 | 2 |
| 12 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | 0.69 | 1 |
| 13 | Bosentan | 0.69 | 1 |
| 14 | piericidin | 0.69 | 1 |
| 15 | bdb 3 4s 4ar 6 hydroxy 4a methyl 1 s methyl 1 2 3 4 4a 9 10 10a octahydro phenanthre | 0.69 | 1 |
| 16 | bdb 4s 4ar 6 hydroxy 4a methyl 1 s methyl 1 2 3 4 4a 9 10 10a octahydro phenanthrene | 0.69 | 1 |
About NR1H3 as a Drug Target
NR1H3 (nuclear receptor subfamily 1 group H member 3) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 16 compounds with documented NR1H3 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
NR1H3 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.