PAK5
MOLECULAR TARGETp21 (RAC1) activated kinase 5
PAK5 (p21 (RAC1) activated kinase 5) is targeted by 15 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting PAK5
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | tozasertib | 4.33 | 75 |
| 2 | ruxolitinib | 4.23 | 68 |
| 3 | nintedanib | 3.61 | 36 |
| 4 | tae 684 | 3.43 | 30 |
| 5 | fedratinib | 3.40 | 29 |
| 6 | jnj 7706621 | 3.09 | 21 |
| 7 | lestaurtinib | 3.04 | 20 |
| 8 | pf 03758309 | 3.00 | 19 |
| 9 | r 406 | 2.83 | 16 |
| 10 | pha 665752 | 2.71 | 14 |
| 11 | kw 2449 | 2.64 | 13 |
| 12 | gsk 690693 | 2.64 | 13 |
| 13 | su 014813 | 2.20 | 8 |
| 14 | alsterpaullone | 0.69 | 1 |
| 15 | kenpaullone | 0.69 | 1 |
About PAK5 as a Drug Target
PAK5 (p21 (RAC1) activated kinase 5) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 15 compounds with documented PAK5 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
PAK5 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.