PDE4A
MOLECULAR TARGETphosphodiesterase 4A
PDE4A (phosphodiesterase 4A) is targeted by 18 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting PDE4A
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Enoximone | 1.10 | 2 |
| 2 | palmidrol [Supplementary Concept] | 0.69 | 1 |
| 3 | Vitamin K 2 | 0.69 | 1 |
| 4 | 8-Bromo Cyclic Adenosine Monophosphate | 0.69 | 1 |
| 5 | Anthralin | 0.69 | 1 |
| 6 | Bufexamac | 0.69 | 1 |
| 7 | Cimetidine | 0.69 | 1 |
| 8 | Daptomycin | 0.69 | 1 |
| 9 | Dequalinium | 0.69 | 1 |
| 10 | Disulfiram | 0.69 | 1 |
| 11 | Ertapenem | 0.69 | 1 |
| 12 | Ethynodiol Diacetate | 0.69 | 1 |
| 13 | Hexachlorophene | 0.69 | 1 |
| 14 | Methoxsalen | 0.69 | 1 |
| 15 | Papaverine | 0.69 | 1 |
| 16 | streptonigrin | 0.69 | 1 |
| 17 | Sulfisomidine | 0.69 | 1 |
| 18 | Troglitazone | 0.69 | 1 |
About PDE4A as a Drug Target
PDE4A (phosphodiesterase 4A) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 18 compounds with documented PDE4A interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
PDE4A inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.