PDE4D
MOLECULAR TARGETphosphodiesterase 4D
PDE4D (phosphodiesterase 4D) is targeted by 25 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting PDE4D
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Thyroxine | 0.69 | 1 |
| 2 | vinpocetine | 0.69 | 1 |
| 3 | Abacavir | 0.69 | 1 |
| 4 | Adenosine Triphosphate | 0.69 | 1 |
| 5 | Amoxapine | 0.69 | 1 |
| 6 | Antazoline | 0.69 | 1 |
| 7 | Bromocriptine | 0.69 | 1 |
| 8 | Bucladesine | 0.69 | 1 |
| 9 | candesartan cilexetil [Supplementary Concept] | 0.69 | 1 |
| 10 | Cladribine | 0.69 | 1 |
| 11 | Clofarabine | 0.69 | 1 |
| 12 | Codeine | 0.69 | 1 |
| 13 | Crizotinib | 0.69 | 1 |
| 14 | Dextrothyroxine | 0.69 | 1 |
| 15 | Dihydroergotamine | 0.69 | 1 |
| 16 | Domperidone | 0.69 | 1 |
| 17 | Gestrinone | 0.69 | 1 |
| 18 | hydrocodone | 0.69 | 1 |
| 19 | Moricizine | 0.69 | 1 |
| 20 | Nortriptyline | 0.69 | 1 |
| 21 | Olmesartan Medoxomil | 0.69 | 1 |
| 22 | Papaverine | 0.69 | 1 |
| 23 | Terlipressin | 0.69 | 1 |
| 24 | Thyroxine | 0.69 | 1 |
| 25 | Troglitazone | 0.69 | 1 |
About PDE4D as a Drug Target
PDE4D (phosphodiesterase 4D) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 25 compounds with documented PDE4D interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
PDE4D inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.