PHKG1
MOLECULAR TARGETphosphorylase kinase catalytic subunit gamma 1
PHKG1 (phosphorylase kinase catalytic subunit gamma 1) is targeted by 21 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting PHKG1
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | gefitinib | 5.67 | 290 |
| 2 | alvocidib | 4.52 | 91 |
| 3 | tozasertib | 4.33 | 75 |
| 4 | vandetanib | 4.30 | 73 |
| 5 | ruxolitinib | 4.23 | 68 |
| 6 | bosutinib | 4.08 | 58 |
| 7 | midostaurin | 3.85 | 46 |
| 8 | nintedanib | 3.61 | 36 |
| 9 | pelitinib | 3.50 | 32 |
| 10 | bms 387032 | 3.47 | 31 |
| 11 | tae 684 | 3.43 | 30 |
| 12 | fedratinib | 3.40 | 29 |
| 13 | dovitinib | 3.09 | 21 |
| 14 | lestaurtinib | 3.04 | 20 |
| 15 | ruboxistaurin | 2.94 | 18 |
| 16 | pha 665752 | 2.71 | 14 |
| 17 | kw 2449 | 2.64 | 13 |
| 18 | su 014813 | 2.20 | 8 |
| 19 | enzastaurin | 2.08 | 7 |
| 20 | sra 737 | 1.95 | 6 |
| 21 | Afatinib | 0.69 | 1 |
About PHKG1 as a Drug Target
PHKG1 (phosphorylase kinase catalytic subunit gamma 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 21 compounds with documented PHKG1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
PHKG1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.