PHOSPHATIDYLINOSITOL
MOLECULAR TARGETPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (human)
PHOSPHATIDYLINOSITOL (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (human)) is targeted by 14 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting PHOSPHATIDYLINOSITOL
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | pictilisib | 4.25 | 69 |
| 2 | ly294002 | 3.85 | 46 |
| 3 | alpelisib | 3.26 | 25 |
| 4 | Wortmannin | 2.94 | 18 |
| 5 | torin 1 | 2.08 | 7 |
| 6 | myricetin-3-O-galactopyranoside [Supplementary Concept] | 1.79 | 5 |
| 7 | Quercetin | 1.61 | 4 |
| 8 | Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as | 1.61 | 4 |
| 9 | Ku 0063794 [Supplementary Concept] | 1.10 | 2 |
| 10 | Sirolimus | 0.69 | 1 |
| 11 | Resveratrol | 0.69 | 1 |
| 12 | butein | 0.69 | 1 |
| 13 | Crizotinib | 0.69 | 1 |
| 14 | Harmine Alkaloid isolated from seeds of PEGANUM HARMALA; ZYGOPHYLLACEAE. It is identical to banisterine, or telepathine, from Banisteria caapi and is | 0.69 | 1 |
About PHOSPHATIDYLINOSITOL as a Drug Target
PHOSPHATIDYLINOSITOL (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (human)) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 14 compounds with documented PHOSPHATIDYLINOSITOL interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
PHOSPHATIDYLINOSITOL inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.